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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP1
All Species:
44.55
Human Site:
Y99
Identified Species:
70
UniProt:
P61764
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61764
NP_001027392.1
594
67569
Y99
K
D
P
P
T
A
K
Y
R
A
A
H
V
F
F
Chimpanzee
Pan troglodytes
XP_001152683
595
67000
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Rhesus Macaque
Macaca mulatta
XP_001095617
580
66142
Y85
K
D
P
P
T
A
K
Y
R
A
A
H
V
F
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Rat
Rattus norvegicus
P61765
594
67550
Y99
K
D
P
P
T
A
K
Y
R
A
A
H
V
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
Y85
K
D
P
P
T
A
K
Y
R
A
A
H
V
F
F
Chicken
Gallus gallus
Q6R748
594
67454
Y99
K
D
P
P
T
S
K
Y
R
A
A
H
V
F
F
Frog
Xenopus laevis
NP_001093335
595
67691
Y99
K
D
P
P
S
S
K
Y
R
A
A
H
V
F
F
Zebra Danio
Brachydanio rerio
NP_001020353
591
67111
Y99
K
D
P
H
S
A
K
Y
K
G
A
H
V
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
Y110
E
N
P
A
R
P
M
Y
R
Y
A
H
V
F
F
Honey Bee
Apis mellifera
XP_396375
585
66573
Y99
S
N
P
T
R
T
S
Y
K
V
A
H
V
Y
F
Nematode Worm
Caenorhab. elegans
P34815
673
76715
Y179
D
Y
C
A
R
N
L
Y
K
C
A
H
V
F
F
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
Y96
K
D
I
N
S
L
Q
Y
K
V
A
H
I
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
K114
T
G
K
S
P
L
Y
K
K
A
F
V
F
F
S
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
R97
M
V
R
P
P
K
Y
R
R
C
H
I
R
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
97.6
N.A.
N.A.
62.7
100
N.A.
93.4
97.9
92.4
86.5
N.A.
63.4
63.9
52.1
60.9
Protein Similarity:
100
81.1
97.6
N.A.
N.A.
80.6
100
N.A.
96.1
99.4
97.9
94.6
N.A.
78
79.6
67.4
77.7
P-Site Identity:
100
53.3
100
N.A.
N.A.
53.3
100
N.A.
100
93.3
86.6
73.3
N.A.
53.3
40
40
46.6
P-Site Similarity:
100
73.3
100
N.A.
N.A.
73.3
100
N.A.
100
100
100
86.6
N.A.
66.6
60
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
34
0
0
0
60
87
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
14
0
0
0
0
0
% C
% Asp:
7
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
14
0
0
0
0
7
0
7
94
87
% F
% Gly:
0
20
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
7
87
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
7
20
0
0
% I
% Lys:
54
0
7
0
0
7
47
7
47
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
14
7
0
0
0
0
0
0
0
7
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
0
7
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
60
14
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
20
0
0
7
54
0
0
0
7
0
0
% R
% Ser:
7
0
0
7
20
14
7
0
0
0
0
0
0
0
7
% S
% Thr:
7
0
14
7
47
7
14
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
14
0
7
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
14
87
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _